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pentobarbital will minimize the level or impact of pimozide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.pentobarbital will reduce the level or effect of celecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unknown.pentobarbital will lower the level or outcome of diazepam by i